I find Gary Sharpe's recent posts to be compelling and it caused me to reflect upon my own inflammation history:
2010 - I developed sudden severe discomfort in my urinary tract, basically the constant sensation of needing to pee which was eventually diagnosed as chronic inflammation of the prostate gland, known as prostatitis.
2012 - I started to develop sudden severe abdominal pain after eating certain foods, which has since been identified as IBS.
2014 - my right index finger started twitching and was eventually diagnosed with Parkinson's in December that year.
To me it now seems apparent this is a pattern of progressive inflammation and fits exactly the pattern described by Gary.
I honestly think that this is game changing thinking for at least my sub type of PD.
As a footnote since starting Sinemet in January I've noticed only minimal benefit.